As far as DE-hopping, it does come with some problems. At the very least, you will have a ton of different apps installed, as each DE will want its own file manager, terminal, etc. At worst, you will get conflicts and it can end up a right mess.
I would personally keep a separate virtual machine or Ventoy USB separate from your main machine, as it will give you the freedom to mess around with different desktops to your heart’s content. If that isn’t an option for whatever reason, then at the very least make sure you create a separate user account for each separate WM/DE you install so that shit doesn’t break.