It’s just a podman/docker container. I’m pretty sure it is unprivileged (you don’t need root). I’ve tried it on both NVIDIA (RTX 3050 Mobile) and AMD (Radeon RX Vega 56) and setting up the distrobox through BoxBuddy (a nice GUI app that makes management easy) I didn’t need to do anything to get the graphics drivers working. I only mentioned BoxBuddy because I haven’t set one up from the command line so I don’t know if it does any initial set up. I haven’t noticed any performance issues (yet).