Some applications can’t display some Unicode strings like s̵t̵r̵o̵k̵e̵, so replacing Markdown element like ~strike~ with Unicode equivalent (s̵t̵r̵o̵k̵e̵ ) may not be a good idea if you want portability. I opened your post in text editors and noticed that neovim-qt drops s̵t̵r̵o̵k̵e̵’s combining characters (issue on Github) and just displays stroke instead of s̵t̵r̵o̵k̵e̵; GUI Emacs with my font settings (Noto) doesn’t combine the characters and displays s-t-r-o-k-e- (as I said, this may depends on font settings).