SimpleX isn't able to share your profile-data between devices. Instead you connect with e.g. the desktop app to the phone to use the phone-profile, but it need to stay online, which can be inconvenient.
With the CLI version you are able to run it on some (private) server and then connect the phone and desktop app to it.
But it is still not really convenient, as you need to establish a tunnel (for example SSH port forwarding) to the server (the clients don't support connecting via internet URL the last time I checked).