Accountant here too (well assistant tax adviser doing mainly accounting) and I have the numpad on a layer on the right hand and often used shortcuts on the left hand. It is really nice and only took me like a week to get comfy with.
The extra shortcuts also help a lot, because they are hardcoded into the software and some of them are pretty dumb (shift+F8 and ctrl+numpad / f.e.).
One thing I haven’t seen in this thread yet is how lower number keys allow for an even split and this ergo boards that allow for better posture, especially for the shoulders.