It’s funny how people overestimate what a person that never gamed can do. OP, Factorio is constant precise clicking with an unintuitive UI if you haven’t played any games. So is Satisfactory and similar others.
Start with things casual gamers play. There is a reason Sims is so popular. If you want to later (muuuch later) introduce her into the FPS genre - Portal 2. It has very little controls to remember, and very rarely is there any action that needs to require dexterity in aiming. Also, Valve invisible tutorials are awesome for new gamers.