It depends. GNOME on Wayland + Nvidia runs great. But if you try the tiling manager camp, you will run into several issues in sway, hyprland. Things like having to use software mouse because insert nvidia excuse and high cpu usage by just moving the mouse.
Well… I don’t know, I would recommend GNOME on Wayland or maybe KDE, haven’t tried the latest Plasma 6 release, but outside that, avoid it.