Certainly, I myself am on a Linux machine with a 1070Ti and a Xeon 1650 processor that’s never left it’s socket since it was placed in there in some factory. I would guess it’s somewhat rare to have a machine such as this because it was originally meant as a workstation (I can tell because the door has handles on the inside that make it an effective shield), and I would guess anyone who does have this set up will have Windows installed on it.
That being said, differences in software between Windows and Linux is slowly becoming irrelevant with the continued development of proton and the various FOSS alternatives (i.e. GIMP replacing Photoshop). For the most part, the only differences these days are certain games from certain studios that for whatever reason decided not to check a box that says “Yes, I want this to work on Linux.” This of course disregards any specialist software that was only ever developed for Windows, which I’ve read numerous examples of.