I word it this way because I’m not an expert, I was reading through a few studies I found on Google and am no way qualified to weigh in on this beyond a cursory glance.
That being said, I’ve heard migraines be described similarly to torture. We can agree to disagree as to whether or not that’s safe (the effects of chronic pain are well documented).
Also
Prolonged treatment with Gonadotropin-Releasing Hormone (GnRH) agonists is known to induce bone loss among prostate cancer patients. However, evidence on the skeletal effects of GnRH antagonists is relatively less well-known. This review aims to examine the effects of GnRH antagonists on bone health. GnRH antagonists are an effective treatment for hormone-dependent conditions, such as advanced prostate cancer and endometriosis. They induce a competitive and reversible GnRH-receptor blockage, thereby suppressing the release of gonadotropins and sex hormones. The sex hormone ablation results in undesirable side effects, including accelerated bone loss. In animal studies, treatment with GnRH antagonists is reported to cause deterioration of bone microstructure. Human clinical trials revealed significant bone loss at the spine, hip and femur in patients treated with GnRH antagonists. Thus, osteoporosis and the resultant fragility fractures pose a significant impact on health and quality of life of GnRH antagonist users. Thus, early preventive measures of bone loss are critical in preventing fractures and its associated morbidity in these patients.
There are certainly other factors to consider, GnRH is used to treat prostate cancer if I’m not mistaken. I have no idea what would happen in an AFAB, and truth be told I’m not going that deep. I don’t think anyone should be telling anyone what they can or can’t put in/do with their bodies, but I’m not sure what to believe about the risk. Reading this would certainly make me second guess taking them considering my family history of arthritis.