Trans youth will no longer be prescribed puberty blockers, NHS England says

Trans youth will no longer be prescribed puberty blockers at NHS England gender identity clinics in a new “blow” to gender-affirming healthcare.

Puberty blockers are a type of medicine that prevent puberty from starting by blocking the hormones – like testosterone and oestrogen – that lead to puberty-related changes in the body. In the case of trans youth, this can delay unwanted physical changes like menstruation, breast growth, voice changes or facial hair growth.

On Tuesday (12 March), NHS England confirmed the medicine, which has been described as “life-saving” medical care for trans youth, will only be available to young people as part of clinical research trials.

The government described the move as a “landmark decision”, Sky News reported. It believed such a move is in the “best interests of the child”.

febra,

Right wing twats trying their best to destroy as many children as they can

fritobugger2017,

Christo-fascists run too many gov’ts

Cold_Brew_Enema,

deleted_by_moderator

    •
    trougnouf,

    I don’t know what I want for dinner and that never stopped me from identifying myself.

    Red_October,

    You know puberty blockers aren’t permanent right? Stop taking them, and then puberty happens. But once you’ve gone through puberty, there’s no undoing that. That’s where the harm is, in forcing someone to undergo changes they know they don’t want.

    mods_are_assholes,

    Anti-trans people will not be swayed by facts, they want their hated other and they’ve made their choice.

    The only thing we can do is try and limit their damage

    DarkroomDoc,

    This is only true of GnRH related medications. Use of hormones as well as more effects. Just to be clear.

    www.ncbi.nlm.nih.gov/pmc/articles/PMC6626312/

    FriendBesto, (edited )

    Fact: Lots of things happening in the UK for those who do not know:

    Why was the Tavistock experiment allowed to go on for so long?

    Hopefully, this will be the end for the cult of trans, which reels in impressionable young people when they aren’t sure who they are

    telegraph.co.uk/…/why-tavistock-experiment-allowe…

    Tavistock transgender clinic shut down by NHS after review finds it is ‘not safe’ for children

    Young people who believe that they are trans will be moved into regional centres which will take a more ‘holistic’ approach to treatment

    telegraph.co.uk/…/tavistock-transgender-clinic-sh…

    “The decision is a response to the interim Cass Review, which warned that medics in the Tavistock had felt “under pressure to adopt an unquestioning affirmative approach” to gender identity rather than going through the normal process of clinic assessment with young people.”

    PS: Do not shot the messenger. I was not the one who carried the investigations nor did the abuse as per described in the articles.

    Adanisi,
    @Adanisi@lemmy.zip avatar

    “Cult of trans”

    Who’s the leader? What’s the goal?

    Also, citing the Torygraph rag instead of actual sources isn’t a good look.

    Tattorack,
    @Tattorack@lemmy.world avatar

    We know so little about the actual process of gender dysphoria. Hormone blockers don’t solve or fix anything, but have been used simply because it’s the only thing that does something. Essentially bringing a blunt instrument to the problem.

    Considering the harmful nature of hormone blockers, I’m for not prescribing puberty blockers to youth. However, only so long as more research is put into it.

    Adanisi,
    @Adanisi@lemmy.zip avatar

    Can you point me to the harmful nature of them?

    jordanlund,
    @jordanlund@lemmy.world avatar

    Hormone blockers are generally used because it’s far easier for people to transition if they haven’t already been smacked around by puberty and it ends up giving a healthier result.

    texastribune.org/…/texas-transgender-kids-transit…

    (I KNOW, right? “Texas Tribune?”)

    “Studies have found that transgender youth who take puberty blockers are significantly less likely to experience lifelong suicidal ideation than those who want the care and don’t get it. And studies show psychological trauma is reduced and life satisfaction increases when people who want transition-related hormone therapy get it.

    Major medical associations support transition-related care. They include the American Academy of Pediatrics, the American Medical Association, the Endocrine Society, the World Medical Association and the World Professional Association for Transgender Health.”

    Korne127,
    @Korne127@lemmy.world avatar

    Best interest of the child my ass. I knew and know so many trans kids that suffer(ed) so much from such awful transphobic laws.
    That’s just purely disgusting and will have horrible consequences for so many people. I am so sorry for every trans kid in England that suffers from this. :(

    UnderpantsWeevil,
    @UnderpantsWeevil@lemmy.world avatar

    40 years of Hollyweird / Music Industry / Olympics trainer agents pumping their youngest stars full of this shit in order to squeeze an extra year or two of revenue out of them? Fine. Cool. Good. No problems detected.

    Some trans youth have a legitimate medical need for deferring puberty, while they come to terms with their gender and sexuality? Fuck you. Prohibited. Go directly to jail.

    Fedizen,

    its almost like the weirdo hollywood guys are in league with the weirdo religious guys.

    UnderpantsWeevil,
    @UnderpantsWeevil@lemmy.world avatar

    By way of the weirdo military guys, most commonly.

    Steak,

    deleted_by_author

    •
    Drivebyhaiku, (edited )

    Honey. We know our shit and we often know it young. I had to go through puberty knowing as I was experiencing it every moment was taking me further and further into a body horror I knew I would never come to terms with. Other trans people my age are very much the same and you know what? A lot of us live with deep lifelong regrets knowing that we have less options to travel the world or exist comfortably in public because of that puberty we knew bone deep right from the get go we never wanted.

    Being trans isn’t subtle. It screams at you, gnaws at your insides how wrong everything is. Particularly when pre-puberty you are able to perfectly pass… And then every minute puberty slowly takes that away from you by inches like a slow bleeding wound until you ache to have what you know you will never effortlessly experience again.

    Ignorance fucking doomed me. Yours will do nothing but doom others.

    Steak,

    deleted_by_author

    •
    Drivebyhaiku,

    Yeah… Is pushing 40 considered young now or do I have to be fucking senile before I count? Take your paternalistic shit and cram it right back up your ass where it came from.

    Phegan,

    TERF island strikes again

    BaardFigur,

    deleted_by_author

    •
    WormFood,

    this is why i haven’t taken my kid to get his supposed ‘broken leg’ fixed. sorry kiddo but i have thoroughly inspected it and determined that the bone angles are within tolerance

    BaardFigur,

    deleted_by_author

    •
    petrol_sniff_king,

    I’ve asked like ten 10 year olds and none of them want me to break their legs; that’s ridiculous.

    whotookkarl,
    @whotookkarl@lemmy.world avatar

    Do you think it would be important to understand the clinical requirements, outcomes, and medical consensus of the previous policy vs a blanket ban before endorsing a ban? Isn’t the point of blockers to slow development so informed consent about transitioning can be made?

    PlantDadManGuy,

    You’re not going to get any sympathy here, but for what it’s worth I agree with you. Some children may be entirely convinced that they know exactly what they want, and two years later they may find out they were completely wrong. I’m a trans ally, but I think children should require the explicit informed consent of their parents for any and all medical treatments including hormone therapy.

    frostysauce,

    Good thing puberty blockers are completely reversible should the child end up being wrong. But if they are not wrong they are spared living through their body changing further into the opposite of their gender.

    5too,

    As I understand it, the rate of post-hormone regret for these kids is extremely low. Like, single or double digits low.

    Adanisi,
    @Adanisi@lemmy.zip avatar

    And to add to that, this isn’t hormone replacement therapy. This is a temporary pause on your hormones.

    PlantDadManGuy,

    I did not say hormone replacement therapy. I said hormone therapy, which is exactly what “pausing puberty” involves.

    Adanisi,
    @Adanisi@lemmy.zip avatar

    Okay then, but that doesn’t really help your position either way.

    Gillick competency be damned.

    Adanisi,
    @Adanisi@lemmy.zip avatar

    Gillick competency be damned.

    TIMMAY,

    I dont want to speak to the social aspect of this issue, but I have to imagine that blocking puberty has some crazy side effects. How long has this medical technology been in use and where can I find studies about it? Again, I know this is sensitive and I am just curious from a biological standpoint.

    BaardFigur,

    deleted_by_author

    •
    TIMMAY,

    That is not what I am saying or implying, as I do not have any information on the subject. Please do not put words in my mouth.

    Cosmicomical,

    Well played, two steps backwards and one step forward. As usual.

    TIMMAY,

    Go fuck yourself, Im not taking any steps in any direction, I was asking for information so that I can further educate myself on a difficult topic.

    Cosmicomical,

    If I fuck myself they’ll think I’m half transgender and take away my rights

    Adanisi,
    @Adanisi@lemmy.zip avatar

    Experimentation… Using drugs tried and tested for decades?

    UnderpantsWeevil,
    @UnderpantsWeevil@lemmy.world avatar

    Okay, but we don’t know what effect it will have on some nosey TERF moms in Sussex who have strong opinions based on an all caps post on Facebook.

    frostysauce,

    It has very few side effects and is completely reversible.

    TranscendentalEmpire,

    blocking puberty has some crazy side effects.

    I’m a provider at a children’s hospital. I specialize in orthopedics and rehabilitation, so I mostly deal with the musculoskeletal system. I have colleagues who would be able to provide a much better and more in depth explanation, but I will do my best.

    Even in orthopedics “hormone blockers” are used fairly frequently. For example the same drugs that people use to transition are utilized to moderate the epiphyseal fusion of growth plates. Puberty is also frequently delayed to moderate the hormone levels of juvenile cancer patients. Or even more increasingly common, to halt the symptoms of precocious puberty in young women.

    The vast majority of juveniles prescribed hormones to delay puberty are for non gender affirming care like cancer. The problem with moderating what medical providers can and can’t treat is that you are assuming you know more about medicine than the a person who went to medical school.

    You may be trying to protect kids, but what ends up happening is an interference of medical care, and usually not the type you intended. If hormone drugs become more monitored, providers may be hesitant, or have a more difficult brine prescribing it.

    The dangers of delaying puberty are very small, when you stop the prescription puberty begins again. Usually the only side effect is excessive growth due to a delay if epiphyseal fusion. In regards to gender affirming care, I will remind people that their providers are looking at total outcomes. Meaning they are factoring in things like the higher potentiality of self harm and suicide.

    DarkroomDoc,

    refers to self as provider

    Definitely not a doctor.

    DaveFuckinMorgan,
    @DaveFuckinMorgan@lemmy.world avatar

    Yeah really. Trust the science. Trust the doctors. NHS says it and it will be so.

    TranscendentalEmpire,

    Provider is actually the preferred terminology in most hospitals nowadays. It helps transition away from physicians being the “captain of the ship” to a more team based medical approach.

    It also helps boost patient confidence in the entire medical team, especially in places like where I work, where there are a lot of residents and PAs doing the bulk of the patient care.

    DarkroomDoc,

    The AMA literally says the opposite:

    www.ama-assn.org/…/a-23-omss-resolution-5.pdf

    The only people pushing “provider” are administrators who would prefer to muddy the waters with regards to who providers care, and the midlevels who benefit.

    TranscendentalEmpire,

    Lol, Idk. Do people go to medical school for the title, or to actually help people?

    I like the team approach, and I think referring to everyone as a provider is especially good for my residents, some of which will occasionally think they know more than a PA-C who’s been here for 30 years, just because they don’t have an MD after their name.

    The only doctors that care about being called doctor are residents who think too highly of themselves, or the dinosaurs who hate patient care and only got into the field for the prestige.

    DarkroomDoc,

    You can feel about it however you’d like, but the term provider was purposely used to justify different care without patients being aware.

    It’s not a matter of a 30 year PA vs a resident, experience certainly matters. But I take issue when you claim medical knowledge because you’re a “provider”, and especially because you work in a pediatric hospital. The role of a pediatric endocrinologist and an ortho PA almost don’t overlap, and the background schooling almost don’t either.

    That’s not to say I’m particularly qualified either (it’s outside my specialty) but you infer that you’re qualified to comment when you and I both know, frankly, you’re not.

    TranscendentalEmpire,

    used to justify different care without patients being aware.

    Lol, you really think a PA is going to provide different care than an MD? What, an MD is going to prescribe PT and bracing when a PA is going to … chop their leg off?

    But I take issue when you claim medical knowledge because you’re a “provider”, and especially because you work in a pediatric hospital.

    Did I not predicate my statement with my lack of speciality? What exactly did I say that was false? If you have problems with the information I stated then say so. But, if all you are doing is appealing to an entirely assumed authority, go kick rocks.

    The role of a pediatric endocrinologist and an ortho PA almost don’t overlap, and the background schooling almost don’t either.

    What? I mean endocrinology doesn’t refer the majority of our patients, but it’s a significant amount… Also, the only information I gave over endocrinology, directly pertains to my field.

    but you infer that you’re qualified to comment when you and I both know, frankly, you’re not.

    Lol, I have no idea how qualified you are, and you have no idea what my qualifications are. However, based on your statement I highly doubt you actually work in patient care. Seems like you’re pretending to be a character of a doctor from a 00’s medical drama.

    mightyfoolish,

    I know therapists and other medical professionals. There is a push to let people see non physicians directly instead of needing a physician to refer you to the person who can obviously help you more.

    TIMMAY,

    Thank you for your reply! This is good information

    _edge,

    That’s why I browse Lemmy. Thank you.

    Lyrl,

    It reduces bone density. Not to unhealthy levels in teens, but there are concerns the lower baseline will increase osteoporosis risk when the patients get to old age.

    They can also only be used for a couple of years. Some non-binary people want to be on them permanently, but doctors won’t prescribe that. Some kids want more time to decide, and unfortunately there isn’t anything safe to use through the full teenage years.

    Omniraptor, (edited )

    Precocious puberty has been a thing forever and the first medications for delaying it by regulating hormones have been around since the 1980s. I think that should be the jumping off point for research. However afaik the same sorts of drugs are also commonly used to treat cancer in adults.

    Here is an article about their use in treating trans people with links to various studies transfemscience.org/articles/puberty-blockers/

    TIMMAY,

    Thank you for the info and link! I will read up

    assassin_aragorn,

    How long has this medical technology been in use and where can I find studies about it?

    Decades. It was there when I was a kid, so like 20 years ago. And it wasn’t new medical technology at the time.

    UnderpantsWeevil,
    @UnderpantsWeevil@lemmy.world avatar

    I have to imagine that blocking puberty has some crazy side effects.

    Sort of the joke. Puberty is what has the crazy side effects.

    Dasus,

    Discovered in 1971, and introduced for medical use in the 1980s.

    “Where can I find studies about it”?

    Have you tried perhaps, idk, a search engine? How do I have a feeling that even if I were to show you the science which agrees that they are safe medications, you’d have an “argument” in which you criticise the info without even reading it.

    People perfectly well know how to look for things online, and when they pretend not to… well, it smells fishy. Fishy, like sealions.

    bigMouthCommie,
    @bigMouthCommie@kolektiva.social avatar

    your accusation of bad faith is, itself, bad faith

    TIMMAY,

    You seem really unpleasant. Good luck out there, friend.

    Dasus,

    You seem really pretentious.

    I hope you get over that. I can give you some contacts if you need a good therapist, buddy.

    ynthrepic,
    @ynthrepic@lemmy.world avatar

    The side effects and risks are worth it when you only get one shot at puberty. If you don’t transition as a pre-pubescent teenager, you will never “pass” as well, especially as a transwoman.

    A really good example of how successful you can be if you’re early is Corey Maison. There are cases of transition regret of course, but they’re still a very small percentage of the total, and that percentage is reduced by puberty blockers giving young people more time to figure out themselves and their own bodies, and to make the choice that’s right for them.

    VR20X6, (edited )

    Yeah, that’s the gravity of things that people don’t seem to understand. Yes, there can be unwanted side effects from puberty blockers, but they are relatively minor. On the other hand, one possible side effect for people that are willing to brave those puberty blocker side effects but aren’t allowed to do so is suicide. This is unfortunately often life or death.

    fidodo,

    There’s some studies that found that bone density could be affected, but considering the suicide rate of trans people I’m going to say that’s a tiny sacrifice for the assurance that you can have the body your brain wants to be in.

    afraid_of_zombies,

    Great Britain should be renamed as Terf Island. Make it descriptive.

    MyFairJulia,
    @MyFairJulia@lemmy.world avatar

    Nah, they prefer prescriptivism. Actually, Terf Island still makes sense from that lens.

    I’m not sure, but there’s a descriptivism/prescriptivism joke in there somewhere.

    Cosmicomical,

    This has nothing to do with the will of the people

    afraid_of_zombies,

    Sure. Voting isn’t a thing in the UK

    Cosmicomical,

    You probably wanted to be ironic, but the irony in this case is misplaced :D

    BilboBargains,

    It’s all part of the NHS War On Mental Health. The plan is remove treatments that conservatives don’t believe in because they can’t see them. They will take those savings and use them to extend the lives of terminally ill people in persistent vegetative states because life is sacred and needs to be protracted and painful.

    Mr_Smiley,

    deleted_by_moderator

    •
    MetaCubed,

    I guess ill be the one to bite.

    How do you consider this good news? All scientific literature indicates that prescribing puberty blockers to trans youth has a large benefit to the state of their current and future mental health, while also causing no harm as once they stop taking them, if they dont further transition, their regular puberty takes over with no decrease in how much they mentally and physically develop (dont forget, these are also regularly prescribed to cis kids too)

    Gigan,
    @Gigan@lemmy.world avatar

    Please link to all relevant scientific literature. Otherwise I’m going to assume you’re just spouting talking points out of your ass because this stuff hasn’t been studied as extensively as you claim.

    frostysauce,

    Please do all the research for me…

    Tattorack,
    @Tattorack@lemmy.world avatar

    The person who makes the claim is responsible for backing it up. So yes, if you’re going to make a going you’re going to do all the research.

    Asking for the relevant scientific backing is a perfectly reasonable thing to ask.

    frostysauce,

    But they asked for all scientific research.

    crapwittyname,

    The second part of what you say (puberty takes over as soon as the blockers are stopped) is not, as far as I’m aware, established. There are huge questions over this. First off, if I decide to come off puberty blockers aged 30, will I then go through puberty? If so, how different will it be to a normal puberty? If not, how long do I take puberty blockers for until I’ve bypassed my puberty? Can we quantify or qualify the potential harms inherent in the treatment? There’re too many unknowns and not enough evidence to support this statement you’ve made. I’ve seen it made before which is why I looked into it.
    I’m not trans myself, but some of the people I love are/were. I love them and I want them to thrive, which is why I’m concerned about the enthusiasm for a seemingly magic bullet which I think has the potential to do a lot of harm if applied without being properly understood.

    throwwyacc,

    I believe the idea of a puberty blocker is to block puberty until 18 pretty much, or early 20s. Then as that person is an adult they can choose to transition, by going through hrt, which is more effective as they haven’t experienced any puberty yet Or they can choose to stop taking the blockers and go through puberty as they would have before

    crapwittyname,

    Thanks for that.
    Annoyingly though I’m getting down votes for expressing a sincerely-held and reasonable concern, so that prevents me from discussing it any further. This topic is unnecessarily toxic online.

    throwwyacc,

    I agree it’s a very charged topic. And tricky to talk about in a lot of circles without being hand waved as a bigot

    It’s understandable though as there are genuinely some people that wouldn’t change their opinion regardless of the research, on both sides mind you

    crapwittyname,

    It’s been a while since I deep dived on this so I will have to go back and have a look at what’s new when I have time.

    Adanisi,
    @Adanisi@lemmy.zip avatar

    Nobody is prescribing blockers for decades.

    MetaCubed,

    What the other user said is correct. Generally puberty blocks are limited to use during adolescence, with use being discontinued in the very early 20’s at the latest. They are a measure to buy time for a person to meet an age of greater maturity so they can make the decision to further transition medically or hormonally. They are not intended to remove sex hormones from the body forever (much to my personal dismay)

    crapwittyname,

    Cheers. I’ll certainly look into that. I’ve not made up my mind (until the medical consensus does), and I’m coming at this from an angle of wanting trans people to have an equal quality of life (and average lifespan) with cis people. Believe it or not.

    Laurentide,
    @Laurentide@pawb.social avatar

    The medical consensus already exists. This isn’t some experimental drug; puberty blockers have been widely prescribed to children for decades. We know how they work, we know they are generally safe, and we know that blocking access to them will result in needless suffering and death.

    Here are the “huge questions” you should really be asking:

    If these drugs are so dangerous, why are people only bringing it up now and not sometime in the 40 years since they entered widespread usage?

    Why are people suddenly claiming that a drug we’ve been using for decades has “too many unknowns” and “not enough evidence” for its safety?

    If all of this controversy is really genuine, and not the result of a moral panic rooted in bigotry, then why is nobody proposing a ban on puberty blockers for cisgender children? How can they be “dangerous” and “untested” for one group of children but safe and effective for a different group of children when both groups are taking them for the same purpose (to delay puberty)?

    If you really care about the welfare of trans people, then you should support giving us the healthcare that we and our doctors say we need.

    crapwittyname,

    If you really care about the welfare of trans people, then you should support giving us the healthcare that we and our doctors say we need.

    I do. And with due respect, you’re just an anonymous poster on an internet forum. Your opinions necessarily carry zero weight. That’s nothing personal because I don’t know you, and I won’t believe your assertions, because that’s not how this works.

    Shotgun_Alice,

    They’re a troll, I’ve seen their account in other threads. If you look at their account they have all down votes. Like they’re trying to collect as many downvotes as they can.

    drmeanfeel,

    All right wingers want for Christmas is increased suicidality of anyone unlike themselves

    Snapz,

    Or probably more accurately if you look at right wing scandals, people that think similarly to them but are brave enough to live their truth and not try to hide behind a bible and pay their reality away.

    Conservatives are cowards. They mainline fear 24/7, they feel list without it.

    Dasus,

    Conservatives are cowards. They mainline fear 24/7, they feel list without it.

    Fear leads to anger. Anger leads to hate. Hate leads to suffering.

    Mouselemming,

    Time to start some really large clinical trials.

    Which wouldn’t be a bad idea anyway, tracking long-term outcomes.

    frezik,

    GnRH was discovered in 1971, and has been available since the '80s. We have a pretty good idea of their long term effects. There could be more about effects on transgender youth in particular, but everything done so far shows it’s safe.

    Jax,

    I’m reading about migraines, joint pain, hot flashes/sweating, decreased libido (which I would expect to take place during treatment) persisting for months after discontinuing use of GnRH. I’m also reading that it can worsen diabetes and osteoporosis?

    Idk, to say that it’s without risk is false I think.

    aurelian,
    @aurelian@lemmy.ml avatar

    How many of these side effects could just be the result of starting puberty after stopping the medication?

    Jax,

    I genuinely don’t know, but is osteoporosis common as a result of puberty?

    Edit:

    later puberty was linked to lower bone mineral density, and that both are risk factors for osteoporosis

    aurelian,
    @aurelian@lemmy.ml avatar

    Also a risk when taking birth control, the question is how severe and can you recover after completing puberty.

    Jax,

    Idk how I feel about kids taking birth control either, is that a normal thing??

    frostysauce,

    If you don’t want kids getting pregnant, yes.

    JasonDJ,

    Wait you mean they have to start taking hormonal birth control before they start having sex?

    Next you’re going to tell me they should get the HPV vaccine before they start having sex too!

    frostysauce,

    😯

    Jax,

    My point is moreso that kids shouldn’t be having sex, but sure yeah. Read into it guys.

    JasonDJ,

    My apologies that you couldn’t get laid in high school.

    Jax, (edited )

    …

    So you’re either suggesting that 12 year olds should be fucking high schoolers, or you’re just too dumb to think about what you said.

    I’ll give you a few minutes.

    Jax,

    I mean I don’t, but more because I don’t like the thought of kids having sex.

    dana,

    You can’t stop people from having sex, so it’s best to give them the education and healthcare necessary to reduce risks.

    Jax,

    I don’t disagree with that. The idea of high schoolers fucking 12 year olds will never sit well with me but sure, it’s probably best they don’t get pregnant as a result of it.

    aurelian,
    @aurelian@lemmy.ml avatar

    Ah I was referring to it as a side effect of birth control in adults. But birth control for ones that have gone through puberty is definitely better than the possibly deadly side effects of child birth and pregnancy.

    SeaJ,

    Safe does not mean no side effects. Those first things would still absolutely qualify it as safe. Those last two you mention seem to be inconclusive by the way you worded it.

    Jax,

    I word it this way because I’m not an expert, I was reading through a few studies I found on Google and am no way qualified to weigh in on this beyond a cursory glance.

    That being said, I’ve heard migraines be described similarly to torture. We can agree to disagree as to whether or not that’s safe (the effects of chronic pain are well documented).

    Also

    Prolonged treatment with Gonadotropin-Releasing Hormone (GnRH) agonists is known to induce bone loss among prostate cancer patients. However, evidence on the skeletal effects of GnRH antagonists is relatively less well-known. This review aims to examine the effects of GnRH antagonists on bone health. GnRH antagonists are an effective treatment for hormone-dependent conditions, such as advanced prostate cancer and endometriosis. They induce a competitive and reversible GnRH-receptor blockage, thereby suppressing the release of gonadotropins and sex hormones. The sex hormone ablation results in undesirable side effects, including accelerated bone loss. In animal studies, treatment with GnRH antagonists is reported to cause deterioration of bone microstructure. Human clinical trials revealed significant bone loss at the spine, hip and femur in patients treated with GnRH antagonists. Thus, osteoporosis and the resultant fragility fractures pose a significant impact on health and quality of life of GnRH antagonist users. Thus, early preventive measures of bone loss are critical in preventing fractures and its associated morbidity in these patients.

    The abstract from this www.eurekaselect.com/article/112477

    There are certainly other factors to consider, GnRH is used to treat prostate cancer if I’m not mistaken. I have no idea what would happen in an AFAB, and truth be told I’m not going that deep. I don’t think anyone should be telling anyone what they can or can’t put in/do with their bodies, but I’m not sure what to believe about the risk. Reading this would certainly make me second guess taking them considering my family history of arthritis.

    🤷‍♂️ idk mane

    prole,

    Yeah, you don’t know… It’s really not what it seems though, and it’s not actually about starting with a conclusion (we shouldn’t be treating trans kids) and then only glomming onto whatever scraps you can find that might indicate that your worldview is correct, while simply ignoring that mountains of evidence to the contrary.

    Definitely not that. You’re just asking questions! And it’s just a coincidence that every time someone tells you why you’re wrong, or asks you for more detail about your arguments, you resort to the whole, “I don’t know, I’m not an expert.” Yeah no shit.

    Jax, (edited )

    So you just didn’t read the part where I said “we shouldn’t be telling people what they can or can’t put in their bodies”, huh?

    My advice to you is to stop letting your emotions dictate your words.

    Edit: oh yeah, after re-reading what I wrote you definitely rage typed this response. Do better.

    Icaria,

    Do yourself a favour and don’t read the possible side effects on the back of the box of paracetamol you bought from the supermarket.

    Jax,

    Yeah I actually do my utmost to avoid taking Acetaminophen.

    Gamoc,

    It’s been around since the 80s, we already know long term outcomes.

    Silentiea,

    Um, excuse me, who said 40 years was long enough? If we don’t have trials that show how people receiving these drugs turned out all the way until they died then we don’t really have long term trials, do we?

    /s

    It’s such a fucking cop out. Nothing will ever be good enough for some people.

    harderian729,

    I wonder what the statistics are of “trans youth” figuring out they’re actually not trans as they get older.

    thesporkeffect,

    I was going to downvote and move on, but instead…

    I have family and friends that are trans, so I have been able to kind of follow their outcomes over the years.

    1. Human gender identity and sexuality does seem to fluctuate somewhat, but it doesn’t seem to me to be random. Some people fully identify as one gender but like to perform as a different one. Other people don’t vary at all. In cases where people “change their mind”, it’s usually because they get discouraged about being able to successfully transition, or they experience severe harassment/workplace discrimination. Just in my anecdotal experience, it’s never because they just randomly decide they no longer want to be trans
    2. No one is getting permanent gender affirmation treatment until they are old enough to know and have been in discussions with doctors for years. I’m sure there are exceptions where some poor 5 year olds parent(s) treated them without medical oversight but it’s not common and no one wants this.
    homoludens,

    So you don’t have to wonder anymore: en.wikipedia.org/wiki/Transsexual#Regrets_and_det…

    Ultraviolet,

    Extremely uncommon. But on the off chance it happens, they just stop taking the puberty blockers and everything proceeds as normal.

    Betch,
    @Betch@lemmy.world avatar

    Basically non-existant but of course when it does happen it gets repeated over and over again. The main reason why anybody detransitions is because of how they get treated during their transition.

    wintermute_oregon,

    About 80% historically. The studies are all over the place. It is mostly resolved at puberty.

    trashgirlfriend,

    This is not only wrong but directly the opposite of the truth

    wintermute_oregon,

    That is documented in studies.

    pubmed.ncbi.nlm.nih.gov/21216800/

    trashgirlfriend,

    Is that the “people who didn’t contact us back are obviously detransitioning” study?

    wintermute_oregon,

    It obvious you’re not trying to have serious conversation since you didn’t read the study and are conflating detransitioning with people who outgrow it. If you don’t understand a topic well enough to talk about it then don’t. I’m done

    NOT_RICK,
    @NOT_RICK@lemmy.world avatar

    didn’t read the study

    It’s behind a paywall…

    FluffyPotato,

    Not in that study. The link you provided only has the abstract but it’s not even about how common detransitioning is.

    It has a sample size of 25 so it couldn’t even draw an average with that but according to the study it’s goal seems to be to document the motives for transitioning for people who go on to transition and the ones who don’t.

    chetradley,

    It’s also the worst type of wrong: the type that has the potential to seriously harm people. Hopefully they retract it instead of continuing to double down.

    Tattorack,
    @Tattorack@lemmy.world avatar

    I take it you have a source you can link to?

    chetradley,

    I’m assuming you’re asking in good faith. I found this type of question to be especially controversial due to the legislation against gender-affirming care, especially puberty blockers. In researching further:

    As others have stated, cases where permanent gender-affirming care was given, such as HRT (hormone therapy) and GRS (genital reconfiguration surgery), instances of regret are incredibly rare, and almost always predicated by lack of support for the individual. They are far outnumbered by instances of trans people undergoing puberty incompatible with their gender, which is itself damaging and irreversible.

    The type of care discussed in this article, GnRH (puberty blockers), has been shown to not have long term consequences, and is only used to delay puberty and the potential long term effects, giving them enough time to make an informed decision about their transition. From the Mayo Clinic:

    GnRH analogues don’t cause permanent physical changes. Instead, they pause puberty. That offers a chance to explore gender identity. It also gives youth and their families time to plan for the psychological, medical, developmental, social and legal issues that may lie ahead…

    When a person stops taking GnRH analogues, puberty starts again.

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