I use it with my focusrite scarlet (2i2 2nd gen) via asio on W11 and it works fine. Running it in windowed mode lets you set the resolution and put it anywhere on your screen you want.
There are lots of walkthroughs online on how you can set up asio. Modding it consists of replacing a single DLL and then adding your settings to a text file.
If you’ve got big boy audio gear, my assumption is that you’re not using RS for learning to play. It’s awesome for picking up new songs or just playing along with songs you love.
Check out customsforge.com for user created content.