At the point the game allows multiple manual saves, rewinding decisions is trivial. There is not much of a point in restricting autosaves too.
The only way a game can enforce permanent decisions is if it only has auto-saves, in which case it could have a couple hidden backup saves just to prevent any issue from ruining people's progress. Even then that's not enough if players are willing to tinker, but at least it's not trivial.
Online saves are an option too but I wouldn't be too fond of a game that is needlessly restricted to online-only just to make decisions permanent.