This study examines OTC anticholinergics use in a group of 3500 people 65 and older in Seattle, Washington at two points in time, an average of 7 years apart.
In that time, 800 individuals developed dementia and they found that anticholinergic use resulted in an increased risk of dementia. There is a dose-dependent relationship as well, the higher the cumulative dose meant a greater risk of developing dementia.
From the article:
“Taking an anticholinergic for the equivalent of three years or more was associated with a 54% higher dementia risk than taking the same dose for three months or less.”
Granted, this study is looking at persons 65 and older, which do have an altered drug metabolism compared to younger persons, but even so it’s not looking good generally for humans to have chronic exposure to drugs like Benadryl.
Diphenhydramine, sold as Benedryl, can cause hallucinations when overdosing. Some people purposefully overdose on Benedryl to hallucinate. “The Hatman” refers to seeing something that looks like a shadowy figure of a person wearing a hat.
My wife once got high on the normal adult dose because my god it seems like anything that crosses the blood brain barrier hits her like a freight train.
Anyway she went on a deranged tirade about how wagon wheel pasta created incels. How the mom eating it causes rectal-vaginal fistulas that contaminate the fetus by introducing the letter “I” into their cells (incel = I in cells). She was crying about how we needed to go to change.org and start a petition to ban wagon wheel pasta.
I never hear good things about it. Mostly hallucinations about spiders and bugs in the corners and other very unsettling things. It’s basically sleep paralysis
Wait. I thought triple C’s was something else. I think it stands for cough, congestion, cold…? I remember taking a blister pack of 8 pills to get high back in the day. Was that off-brand benadryl?
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